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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYNCRIP
All Species:
31.82
Human Site:
S249
Identified Species:
70
UniProt:
O60506
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60506
NP_001153145.1
623
69603
S249
N
N
R
L
F
V
G
S
I
P
K
S
K
T
K
Chimpanzee
Pan troglodytes
XP_518621
772
85108
S398
N
N
R
L
F
V
G
S
I
P
K
S
K
T
K
Rhesus Macaque
Macaca mulatta
XP_001088724
605
67357
S249
N
N
R
L
F
V
G
S
I
P
K
S
K
T
K
Dog
Lupus familis
XP_532223
813
90830
S457
N
N
R
L
F
V
G
S
I
P
K
S
K
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMK9
623
69614
S249
N
N
R
L
F
V
G
S
I
P
K
S
K
T
K
Rat
Rattus norvegicus
Q7TP47
533
59692
Q211
E
D
H
K
T
A
A
Q
A
R
R
R
L
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510103
623
69613
S249
N
N
R
L
F
V
G
S
I
P
K
S
K
T
K
Chicken
Gallus gallus
NP_001006309
633
71002
S252
N
N
R
L
F
V
G
S
I
P
K
N
K
T
K
Frog
Xenopus laevis
NP_001084953
624
69290
S253
N
N
R
L
F
V
G
S
I
P
K
S
K
T
K
Zebra Danio
Brachydanio rerio
Q08BH5
510
56941
R220
E
E
T
M
Q
R
V
R
V
L
Y
V
R
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q08473
344
36166
K57
G
Q
R
D
D
D
R
K
L
F
V
G
G
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.6
96.1
73.6
N.A.
99.6
85
N.A.
98.8
81.6
93.5
30.6
N.A.
21.5
N.A.
N.A.
N.A.
Protein Similarity:
100
80.6
96.3
73.8
N.A.
100
85.5
N.A.
99.5
90.8
96.7
42.3
N.A.
31.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
100
93.3
100
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
100
100
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
10
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
19
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
73
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
73
0
0
0
0
10
10
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
10
0
0
73
0
73
0
73
% K
% Leu:
0
0
0
73
0
0
0
0
10
10
0
0
10
10
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
73
73
0
0
0
0
0
0
0
0
0
10
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
73
0
0
0
0
0
% P
% Gln:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
82
0
0
10
10
10
0
10
10
10
10
0
0
% R
% Ser:
0
0
0
0
0
0
0
73
0
0
0
64
0
0
19
% S
% Thr:
0
0
10
0
10
0
0
0
0
0
0
0
0
73
0
% T
% Val:
0
0
0
0
0
73
10
0
10
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _